URB-602
| URB602 Basic information |
| Product Name: | URB602 |
| Synonyms: | URB602;Biphenyl-3-yl Carbamic Acid, Cyclohexyl Ester;cyclohexyl biphenyl-3-ylcarbaMate;N-[1,1'-Biphenyl]-3-yl-;Cyclohexyl [1,1'-biphenyl]-3-ylcarbaMate |
| CAS: | 565460-15-3 |
| MF: | C19H21NO2 |
| MW: | 295.38 |
| EINECS: | |
| Product Categories: | All Inhibitors;Inhibitors;Pharmaceutical intermediate;Aromatics;Research Chemical;Chemical for Research |
| Mol File: | 565460-15-3.mol |
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| URB602 Chemical Properties |
| mp | 122-123°C |
| Safety Information |
| URB602 Usage And Synthesis |
| Chemical Properties | Off-White Solid |
| Usage | URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 , or other lipid metabolizing enzymes such as diacylglycerol lipase or |
| Usage | URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 μM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 μM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management. |
